710-1006

completed

Safety and Efficacy of the Xanomeline Transdermal Therapeutic System (TTS) in Patients with Mild to Moderate Alzheimers Disease. · Phase II
710 (USA) · Dr. Silva
consented 2013-02-10

AEs

Serious

Dropout signal

–

Adverse events

mild assessed

Mild CONTUSION — outcome: NOT RECOVERED/NOT RESOLVED; onset 2013-08-08 (study day 180.0); relationship: NONE

mild assessed

Mild DIZZINESS — outcome: RECOVERED/RESOLVED; onset 2013-02-18 (study day 9.0); relationship: NONE

mild assessed

Mild DIZZINESS — outcome: RECOVERED/RESOLVED; onset 2013-04-16 (study day 66.0); relationship: NONE

moderate assessed

Moderate FACIAL BONES FRACTURE — outcome: NOT RECOVERED/NOT RESOLVED; onset 2013-08-08 (study day 180.0); relationship: NONE

mild assessed

Mild FALL — outcome: RECOVERED/RESOLVED; onset 2013-08-08 (study day 180.0); relationship: NONE

moderate assessed

Moderate NEPHROLITHIASIS — outcome: RECOVERED/RESOLVED; onset 2013-04-17 (study day 67.0); relationship: NONE

moderate assessed

Moderate PRURITUS — outcome: NOT RECOVERED/NOT RESOLVED; onset 2013-05-18 (study day 98.0); relationship: POSSIBLE

mild assessed

Mild SALIVARY HYPERSECRETION — outcome: NOT RECOVERED/NOT RESOLVED; onset 2013-03-01 (study day 20.0); relationship: POSSIBLE

moderate assessed

Moderate SINUS BRADYCARDIA — outcome: NOT RECOVERED/NOT RESOLVED; onset 2013-06-29 (study day 140.0); relationship: REMOTE

moderate assessed

Moderate SINUS BRADYCARDIA — outcome: RECOVERED/RESOLVED; onset 2013-06-29 (study day 140.0); relationship: REMOTE

mild assessed

Mild SKIN IRRITATION — outcome: NOT RECOVERED/NOT RESOLVED; onset 2013-03-01 (study day 20.0); relationship: POSSIBLE

mild assessed

Mild URINARY TRACT INFECTION — outcome: RECOVERED/RESOLVED; onset 2013-04-17 (study day 67.0); relationship: NONE

Data queries

No data queries.